PARP10

Across TCGA cell cohorts, PARP10 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PARP10-associated genes across cancer lineages are CFAP97D2, OR1A1, and SULT1C3. Each is linked with PARP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both PARP10-to-partner and partner-to-PARP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFAP97D2 grouped by PARP10-low versus PARP10-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARP10→partner) and Y-score (partner→PARP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CFAP97D2 →	+0.023	+3.392	<.001	.007	3	1
SOFT_TISSUE	OR1A1 →	+0.013	+5.977	<.001	.001	3	1
PANCREAS	SULT1C3 →	+0.181	+4.491	<.001	.003	3	1
OVARY	MS4A10 →	+0.013	+5.196	<.001	.005	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.017	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR2V2 →	+0.040	+4.544	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

CFAP97D2 by PARP10 expression — OESOPHAGUS

Explore this box plot interactively →