PARD6A

Across TCGA patient cohorts, PARD6A RNA expression is significantly associated with the protein abundance of many other proteins, with 12,995 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PARD6A-associated proteins across cancer lineages are MYEF2, TERF2IP, and FTO. Each is linked with PARD6A in more than 5 cancer types. Because this analysis shows association rather than direction, both PARD6A-to-partner and partner-to-PARD6A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARD6A versus MYEF2 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PARD6A→partner) and Y-score (partner→PARD6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MYEF2 →	+0.779	+0.593	<.001	<.001	3	6
LSCC	TERF2IP →	+0.258	+0.581	.002	.003	3	5
GBM	FTO →	+0.370	+0.762	<.001	<.001	3	5
LSCC	MYEF2_S17 →	+0.704	+0.510	<.001	<.001	3	5
OV	NAE1 →	+0.274	+0.528	<.001	.002	3	4
LSCC	ZMAT2 →	+0.263	+0.705	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,995 associations by consensus.

PARD6A vs MYEF2 — LSCC

Explore this scatter interactively →