PARD6A

Across TCGA patient cohorts, PARD6A protein abundance is significantly associated with the RNA expression of many other genes, with 12,413 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARD6A-associated genes across cancer lineages are PRODH, SEZ6L, and SEPTIN3. Each is linked with PARD6A in more than 1 cancer types. Because this analysis shows association rather than direction, both PARD6A-to-partner and partner-to-PARD6A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARD6A versus PRODH in GBM, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARD6A→partner) and Y-score (partner→PARD6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.868	+0.370	.002	<.001	3	1
GBM	SEZ6L →	+2.521	+0.485	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.402	+0.484	.002	<.001	3	1
GBM	XBP1 →	-0.651	-0.495	.001	.003	3	1
GBM	RASL10A →	+1.055	+0.422	<.001	<.001	3	1
GBM	SYNGR1 →	+1.253	+0.419	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,413 associations by consensus.

PARD6A vs PRODH — GBM

Explore this scatter interactively →