PARD6A

Across TCGA patient cohorts, PARD6A protein abundance is significantly associated with the protein abundance of many other proteins, with 23,926 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PARD6A-associated proteins across cancer lineages are RCN1, REEP1, and REEP1_S152. Each is linked with PARD6A in more than 1 cancer types. Because this analysis shows association rather than direction, both PARD6A-to-partner and partner-to-PARD6A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PARD6A versus RCN1 in GBM, with a Pearson correlation of -0.51.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PARD6A→partner) and Y-score (partner→PARD6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RCN1 →	-0.700	-0.599	<.001	<.001	3	1
GBM	REEP1 →	+1.293	+0.609	<.001	<.001	3	1
GBM	REEP1_S152 →	+0.652	+0.433	<.001	<.001	3	1
GBM	REEP1_S192 →	+0.928	+0.339	<.001	.002	3	1
GBM	RELB →	-0.523	-0.463	<.001	<.001	3	1
GBM	RELCH →	+0.350	+0.452	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,926 associations by consensus.

PARD6A vs RCN1 — GBM

Explore this scatter interactively →