PARD6A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PARD6A mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible PARD6A-associated genes across cancer lineages are Th1 cells. Each is linked with PARD6A in more than 1 cancer types. Because this analysis shows association rather than direction, both PARD6A-to-partner and partner-to-PARD6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Th1 cells grouped by PARD6A-low versus PARD6A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PARD6A→partner) and Y-score (partner→PARD6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCATh1 cells →-0.116-2.992.029.03611
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Th1 cells by PARD6A expression — BLCA

Box plot of Th1 cells in PARD6A-low vs PARD6A-high samples in BLCA.

Explore this box plot interactively →

Exploration