PARD6A

Across TCGA cell cohorts, PARD6A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,899 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PARD6A-associated GO terms across cancer lineages are Collagen fibril organization, Extracellular matrix organization, and Complement activation, classical pathway. Each is linked with PARD6A in more than 9 cancer types. Because this analysis shows association rather than direction, both PARD6A-to-partner and partner-to-PARD6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen fibril organization grouped by PARD6A-low versus PARD6A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PARD6A→partner) and Y-score (partner→PARD6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Collagen fibril organization →	-0.436	-1.811	<.001	<.001	3	10
BONE	Extracellular matrix organization →	-0.254	-1.822	<.001	<.001	3	9
LIVER	Complement activation, classical pathway →	-1.288	-1.098	.007	.001	3	9
BONE	Collagen metabolic process →	-0.281	-1.653	<.001	<.001	3	9
BLOOD_Leukemia	Regulation of extracellular matrix organization →	-0.060	-0.884	.001	<.001	3	9
BONE	Regulation of vitamin D biosynthetic process →	-0.992	-1.219	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,899 associations by consensus.

Collagen fibril organization by PARD6A expression — BONE

Explore this box plot interactively →