PALLD-AS1

Across TCGA patient cohorts, PALLD-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,726 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PALLD-AS1-associated GO terms across cancer lineages are Negative regulation of apoptotic signaling pathway, Osteoblast differentiation, and Skeletal system morphogenesis. Each is linked with PALLD-AS1 in more than 13 cancer types. Because this analysis shows association rather than direction, both PALLD-AS1-to-partner and partner-to-PALLD-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of apoptotic signaling pathway grouped by PALLD-AS1-low versus PALLD-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PALLD-AS1→partner) and Y-score (partner→PALLD-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of apoptotic signaling pathway →	+0.056	+0.415	.002	<.001	3	14
ESCA	Osteoblast differentiation →	+0.050	+0.413	<.001	<.001	3	14
STAD	Skeletal system morphogenesis →	+0.046	+0.245	<.001	<.001	3	14
STAD	Bone development →	+0.051	+0.227	<.001	<.001	3	14
STAD	Telomere maintenance via telomere lengthening →	+0.049	+0.214	<.001	<.001	3	13
ESCA	Peptidyl-lysine modification →	+0.056	+0.468	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,726 associations by consensus.

Negative regulation of apoptotic signaling pathway by PALLD-AS1 expression — ESCA

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