PALLD-AS1

Across TCGA pan-cancer cohorts, PALLD-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated PALLD-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PALLD-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PALLD-AS1 expression acts as an unfavorable survival marker, although some lineages such as LAML and UCEC show a favorable association.

ACC, KIRC, and LAML are the cancer types where PALLD-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.039	0.778	<.001	108	view →
KIRC	DFS	Tertile	IV	0.372	0.663	.003	102	view →
LAML	DFS	Tertile	All	0.738	0.539	.028	36	view →
THCA	OS	Quartile	III,IV	0.934	0.985	.002	28	view →
COAD	OS	Tertile	III,IV	0.235	0.710	.005	27	view →
UCEC	OS	Quartile	All	0.963	0.914	.023	14	view →
DLBC	DFS	Tertile	II,III,IV	0.022	0.800	<.001	9	view →
GBM	OS	Tertile	All	0.286	0.434	.032	9	view →
SKCM	OS	Tertile	III,IV	0.567	0.812	.028	9	view →
HNSC	DFS	Tertile	All	0.680	0.580	.024	9	view →
PAAD	OS	Tertile	All	0.240	0.522	.036	6	view →
STAD	OS	Median	IV	0.643	0.354	.030	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

PALLD-AS1–ACC (DFS)

Open the ACC breakdown →