PALLD-AS1

Across TCGA pan-cancer cohorts, PALLD-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of PALLD-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where PALLD-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PALLD-AS1 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.

UCEC, THCA, and HNSC are the cancer types where PALLD-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PALLD-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	+0.310	.035	4	view →
THCA	Female	All	−0.176	<.001	3	view →
HNSC	Female	All	+0.077	.016	2	view →
KIRP	Male	All	−0.025	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

PALLD-AS1–UCEC

Open the UCEC breakdown →