PAGR1

Across TCGA patient cohorts, PAGR1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,010 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PAGR1-associated genes across cancer lineages are ACD, MTERF2, and RRAS. Each is linked with PAGR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PAGR1-to-partner and partner-to-PAGR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PAGR1 versus ACD in OV, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAGR1→partner) and Y-score (partner→PAGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ACD →	+1.227	+0.513	.001	.009	3	4
LSCC	MTERF2 →	+0.415	+0.304	.001	.001	3	4
BRCA	RRAS →	-0.750	-0.566	.001	.009	3	4
CCRCC	LHFPL2 →	-0.775	-0.308	<.001	.002	3	4
OV	POLA1 →	+1.014	+0.489	.002	.008	3	3
OV	RBBP7 →	+0.578	+0.478	.006	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,010 associations by consensus.

PAGR1 vs ACD — OV

Explore this scatter interactively →