Across TCGA patient cohorts, PAGE3 mutation is significantly associated with the RNA expression of many other genes, with 414 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PAGE3-associated genes across cancer lineages are NDUFA5P4, RN7SL745P, and MIR6829. Each is linked with PAGE3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAGE3-to-partner and partner-to-PAGE3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAGE3→partner) and Y-score (partner→PAGE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NDUFA5P4 →	+0.160	+6.111	<.001	.002	3	2
UCEC	RN7SL745P →	+0.341	+3.090	.001	<.001	3	2
LUSC	MIR6829 →	+0.851	+3.970	<.001	.003	3	2
SKCM	RNA5SP21 →	+0.417	+4.215	.002	.009	3	2
COAD	RNU6-264P →	+0.566	+6.392	<.001	.001	3	2
BRCA	RN7SL539P →	+0.079	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 414 associations by consensus.

Exploration

PAGE3 survival (RNA) · tumor vs normal (RNA) · all PAGE3 data types