Across TCGA cell cohorts, PAGE3 RNA expression is significantly associated with the mutation status of many other genes, with 81 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PAGE3-associated genes across cancer lineages are PITPNM2, SHISA6, and NPFFR2. Each is linked with PAGE3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PAGE3-to-partner and partner-to-PAGE3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PAGE3→partner) and Y-score (partner→PAGE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PITPNM2 →	+4.058	+0.065	.009	<.001	3	2
BLOOD_Leukemia	SHISA6 →	+3.969	+0.066	.009	<.001	3	2
BLOOD_Lymphoma	NPFFR2 →	+5.643	+0.105	.002	<.001	3	2
OVARY	SASH3 →	+4.222	+0.020	.006	<.001	3	2
OVARY	PTPRF →	+4.222	+0.020	.006	<.001	3	2
BLOOD_Lymphoma	LRP2 →	+2.769	+0.027	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

Exploration

PAGE3 survival (RNA) · tumor vs normal (RNA) · all PAGE3 data types