P3R3URF

Across TCGA patient cohorts, P3R3URF RNA expression is significantly associated with the go_rna of many other GO terms, with 5,316 significant associations in total. STAD shows the largest number of these associations.

The most reproducible P3R3URF-associated GO terms across cancer lineages are Tetrapyrrole biosynthetic process, Regulation of receptor-mediated endocytosis, and Glycolytic process. Each is linked with P3R3URF in more than 6 cancer types. Because this analysis shows association rather than direction, both P3R3URF-to-partner and partner-to-P3R3URF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tetrapyrrole biosynthetic process grouped by P3R3URF-low versus P3R3URF-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P3R3URF→partner) and Y-score (partner→P3R3URF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Tetrapyrrole biosynthetic process →	+0.107	+0.071	<.001	<.001	3	7
STAD	Regulation of receptor-mediated endocytosis →	+0.082	+0.033	<.001	<.001	3	6
STAD	Glycolytic process →	+0.106	+0.065	<.001	<.001	3	6
STAD	Membrane lipid biosynthetic process →	+0.081	+0.060	<.001	<.001	3	5
STAD	Golgi lumen acidification →	+0.106	+0.057	<.001	<.001	3	5
STAD	Regulation of mitochondrial gene expression →	+0.113	+0.072	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,316 associations by consensus.

Tetrapyrrole biosynthetic process by P3R3URF expression — STAD

Explore this box plot interactively →