Q-omics provides the consensus-scored P3R3URF profile across patient tissues and cancer cell-line models. P3R3URF expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, P3R3URF is differentially expressed in 2, with the highest sampling consensus in KIRC. Additionally, P3R3URF RNA expression shows 5,316 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, and STAD as cancer lineages where P3R3URF shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for P3R3URF — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes P3R3URF survival associations across molecular data types. P3R3URF RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible P3R3URF RNA expression–survival associations across cancer types. High P3R3URF expression shows unfavorable associations in KIRC, CESC, OV, UCEC, STAD and SARC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .007). Together, the overview and detailed table identify KIRC as the clearest survival context for P3R3URF RNA expression.
This table summarizes P3R3URF tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for P3R3URF. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. P3R3URF shows lower tumor expression in KIRC and higher tumor expression in BRCA. The KIRC box plot shows higher P3R3URF RNA expression in normal versus tumor tissue (log2 FC = −0.049, t-test p = .002).
This table shows molecular features associated with P3R3URF in patient tissues and cancer cell lines. In patient samples, P3R3URF shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
