P2RY8

Across TCGA patient cohorts, P2RY8 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,510 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible P2RY8-associated proteins across cancer lineages are RASAL3, RCSD1, and SPN_S355. Each is linked with P2RY8 in more than 9 cancer types. Because this analysis shows association rather than direction, both P2RY8-to-partner and partner-to-P2RY8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, P2RY8 versus RASAL3 in LSCC, with a Pearson correlation of 0.85.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY8→partner) and Y-score (partner→P2RY8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RASAL3 →	+0.578	+1.114	<.001	<.001	3	10
HNSC	RCSD1 →	+0.668	+0.934	<.001	<.001	3	10
OV	SPN_S355 →	+1.219	+1.094	<.001	<.001	3	10
GBM	ABI3 →	+0.503	+0.950	<.001	<.001	3	10
BRCA	GIMAP7 →	+0.734	+0.876	<.001	<.001	3	10
HNSC	GIMAP8 →	+0.630	+0.918	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,510 associations by consensus.

P2RY8 vs RASAL3 — LSCC

Explore this scatter interactively →