P2RY11

Across TCGA patient cohorts, P2RY11 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,101 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible P2RY11-associated proteins across cancer lineages are RAVER1, KEAP1, and RRBP1. Each is linked with P2RY11 in more than 3 cancer types. Because this analysis shows association rather than direction, both P2RY11-to-partner and partner-to-P2RY11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, P2RY11 versus RAVER1 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY11→partner) and Y-score (partner→P2RY11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAVER1 →	+0.279	+0.422	.001	<.001	3	4
LSCC	KEAP1 →	+0.439	+0.629	<.001	<.001	3	4
LSCC	RRBP1 →	-0.424	-0.641	<.001	<.001	3	4
UCEC	SLC12A4 →	-0.333	-0.585	.003	.002	3	4
COAD	FBXO2 →	-0.977	-0.544	<.001	<.001	3	3
LUAD	PPIB →	-0.277	-0.340	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,101 associations by consensus.

P2RY11 vs RAVER1 — GBM

Explore this scatter interactively →