P2RY11

Across TCGA pan-cancer cohorts, P2RY11 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated P2RY11 data layer compared with 3 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher P2RY11 RNA is associated with better overall survival. In most high-consensus cancer types, elevated P2RY11 expression acts as an unfavorable survival marker, although some lineages such as BLCA and UVM show a favorable association.

BLCA, KIRC, and ACC are the cancer types where P2RY11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	III,IV	0.674	0.480	.001	106	view →
KIRC	DFS	Quartile	II,III,IV	0.382	0.623	<.001	94	view →
ACC	DFS	Median	All	0.361	0.796	<.001	91	view →
UVM	OS	Median	All	0.697	0.375	.006	51	view →
UCS	OS	Median	II,III,IV	0.209	0.630	.001	50	view →
LGG	DFS	Median	All	0.652	0.818	<.001	50	view →
COAD	OS	Quartile	IV	0.323	0.774	.003	30	view →
PRAD	DFS	Tertile	All	0.679	0.944	<.001	24	view →
UCEC	DFS	Tertile	All	0.709	0.619	.003	24	view →
LUAD	DFS	Quartile	IV	0.533	0.922	.013	18	view →
SKCM	DFS	Quartile	All	0.779	0.652	.003	16	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

P2RY11–BLCA (OS)

Open the BLCA breakdown →