P2RY11

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, P2RY11 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible P2RY11-associated genes across cancer lineages are p70-S6K_pT389. Each is linked with P2RY11 in more than 1 cancer types. Because this analysis shows association rather than direction, both P2RY11-to-partner and partner-to-P2RY11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p70-S6K_pT389 grouped by P2RY11-low versus P2RY11-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY11→partner) and Y-score (partner→P2RY11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMp70-S6K_pT389 →+0.233+3.169.009.01931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

p70-S6K_pT389 by P2RY11 expression — SKCM

Box plot of p70-S6K_pT389 in P2RY11-low vs P2RY11-high samples in SKCM.

Explore this box plot interactively →

Exploration