P2RY11

Across TCGA cell cohorts, P2RY11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,648 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible P2RY11-associated GO terms across cancer lineages are Energy coupled proton transmembrane transport, against electrochemical gradient, Electron transport coupled proton transport, and Nucleic acid catabolic process. Each is linked with P2RY11 in more than 12 cancer types. Because this analysis shows association rather than direction, both P2RY11-to-partner and partner-to-P2RY11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy coupled proton transmembrane transport, against electrochemical gradient grouped by P2RY11-low versus P2RY11-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY11→partner) and Y-score (partner→P2RY11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.098	+1.556	<.001	<.001	3	13
OESOPHAGUS	Electron transport coupled proton transport →	+0.098	+1.556	<.001	<.001	3	13
BONE	Nucleic acid catabolic process →	+0.072	+1.522	<.001	.003	3	13
OVARY	Neuronal signal transduction →	+1.127	+1.196	<.001	<.001	3	13
BONE	Regulation of chromatin organization →	+0.131	+1.590	<.001	.002	3	13
BONE	Cytoplasm protein quality control →	+0.170	+1.827	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,648 associations by consensus.

Energy coupled proton transmembrane transport, against electrochemical gradient by P2RY11 expression — OESOPHAGUS

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