P2RY10

Across TCGA cell cohorts, P2RY10 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible P2RY10-associated genes across cancer lineages are SLC10A2, ZNF99, and TEX26. Each is linked with P2RY10 in more than 1 cancer types. Because this analysis shows association rather than direction, both P2RY10-to-partner and partner-to-P2RY10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC10A2 grouped by P2RY10-low versus P2RY10-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RY10→partner) and Y-score (partner→P2RY10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SLC10A2 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	ZNF99 →	+0.023	+4.906	<.001	.006	3	1
BLOOD_Leukemia	TEX26 →	+0.026	+4.539	<.001	.007	3	1
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	1
OVARY	PPY →	+0.201	+4.029	<.001	.009	3	1
OVARY	KRTAP11-1 →	+0.105	+4.807	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

SLC10A2 by P2RY10 expression — OESOPHAGUS

Explore this box plot interactively →