P2RY10

Across TCGA pan-cancer cohorts, P2RY10 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of P2RY10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where P2RY10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types P2RY10 is over-expressed in tumor, although a few such as COAD and LUSC show the opposite, repressed pattern.

KIRC, COAD, and LUSC are the cancer types where P2RY10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in P2RY10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+1.485	<.001	11	view →
COAD	All	IV	−1.494	<.001	10	view →
LUSC	All	All	−0.723	<.001	7	view →
BRCA	All	All	+0.653	<.001	4	view →
THCA	All	All	−0.627	.011	2	view →
LUAD	All	All	+0.475	.007	2	view →
KICH	All	All	−0.376	.033	2	view →
ESCA	All	All	+0.936	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

P2RY10–KIRC

Open the KIRC breakdown →