P2RX5-TAX1BP3

Across TCGA cell cohorts, P2RX5-TAX1BP3 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible P2RX5-TAX1BP3-associated genes across cancer lineages are SLC32A1, TCF21, and HCN4. Each is linked with P2RX5-TAX1BP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both P2RX5-TAX1BP3-to-partner and partner-to-P2RX5-TAX1BP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC32A1 grouped by P2RX5-TAX1BP3-low versus P2RX5-TAX1BP3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RX5-TAX1BP3→partner) and Y-score (partner→P2RX5-TAX1BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC32A1 →	+0.617	+3.901	<.001	.006	3	1
BLOOD_Leukemia	TCF21 →	+0.015	+3.705	<.001	.007	3	1
BLOOD_Leukemia	HCN4 →	+0.037	+3.855	.002	.007	3	1
BLOOD_Leukemia	LRIT1 →	+0.032	+4.269	<.001	.002	3	1
BLOOD_Leukemia	NPFFR1 →	+0.015	+4.037	<.001	.004	3	1
BLOOD_Leukemia	C16orf92 →	+0.126	+4.037	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

SLC32A1 by P2RX5-TAX1BP3 expression — BLOOD_Leukemia

Explore this box plot interactively →