P2RX5-TAX1BP3

Across TCGA pan-cancer cohorts, P2RX5-TAX1BP3 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of P2RX5-TAX1BP3’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where P2RX5-TAX1BP3 RNA is repressed in tumor relative to normal tissue. In most cancer types P2RX5-TAX1BP3 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and KIRC are the cancer types where P2RX5-TAX1BP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in P2RX5-TAX1BP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	IV	−0.713	<.001	11	view →
KICH	Female	All	−0.506	<.001	10	view →
KIRC	Male	II,III,IV	−0.217	<.001	9	view →
LUAD	Female	II,III,IV	−0.350	<.001	8	view →
BRCA	All	III,IV	−0.173	<.001	6	view →
HNSC	All	III,IV	+0.114	.007	6	view →
CHOL	All	All	+0.505	<.001	5	view →
READ	All	All	−0.213	.003	5	view →
UCEC	All	II,III,IV	+0.287	.024	4	view →
STAD	All	II,III,IV	+0.187	.005	4	view →
LUSC	All	All	−0.122	.001	3	view →
COAD	Male	All	−0.118	.005	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

P2RX5-TAX1BP3–THCA

Open the THCA breakdown →