P2RX5-TAX1BP3

Across TCGA pan-cancer cohorts, P2RX5-TAX1BP3 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated P2RX5-TAX1BP3 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher P2RX5-TAX1BP3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated P2RX5-TAX1BP3 expression acts as an unfavorable survival marker, although some lineages such as PAAD and KIRC show a favorable association.

ACC, PAAD, and KIRC are the cancer types where P2RX5-TAX1BP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.271	0.619	<.001	70	view →
PAAD	DFS	Tertile	All	0.413	0.218	.001	33	view →
KIRC	DFS	Median	All	0.733	0.511	<.001	28	view →
MESO	DFS	Quartile	IV	0.124	0.535	.013	22	view →
THYM	OS	Median	All	1.000	0.783	.006	18	view →
LGG	DFS	Tertile	All	0.882	0.728	.003	17	view →
KIRP	DFS	Quartile	All	0.979	0.872	.010	12	view →
COAD	DFS	Tertile	IV	0.372	0.729	.008	10	view →
GBM	DFS	Median	All	0.365	0.216	.029	9	view →
UVM	OS	Tertile	III,IV	0.420	0.874	.017	9	view →
LIHC	OS	Median	All	0.636	0.734	.034	8	view →
SKCM	OS	Quartile	IV	0.820	0.277	.038	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

P2RX5-TAX1BP3–ACC (DFS)

Open the ACC breakdown →