P2RX4

Across TCGA patient cohorts, P2RX4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,073 significant associations in total. GBM shows the largest number of these associations.

The most reproducible P2RX4-associated proteins across cancer lineages are PRKAA2_S491, RENBP, and ICAM1. Each is linked with P2RX4 in more than 4 cancer types. Because this analysis shows association rather than direction, both P2RX4-to-partner and partner-to-P2RX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, P2RX4 versus PRKAA2_S491 in HNSC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RX4→partner) and Y-score (partner→P2RX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PRKAA2_S491 →	+1.507	+0.434	<.001	.009	3	4
GBM	RENBP →	+0.518	+0.343	<.001	<.001	3	4
GBM	ICAM1 →	+0.470	+0.297	.004	.007	2	5
GBM	GLTP →	+0.529	+0.267	<.001	.003	3	4
BRCA	HID1 →	+0.593	+0.615	<.001	<.001	3	4
GBM	AHDC1 →	-0.266	-0.331	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,073 associations by consensus.

P2RX4 vs PRKAA2_S491 — HNSC

Explore this scatter interactively →