P2RX4

Across TCGA patient cohorts, P2RX4 protein abundance is significantly associated with the RNA expression of many other genes, with 14,484 significant associations in total. GBM shows the largest number of these associations.

The most reproducible P2RX4-associated genes across cancer lineages are VRK1, GINS1, and TICRR. Each is linked with P2RX4 in more than 4 cancer types. Because this analysis shows association rather than direction, both P2RX4-to-partner and partner-to-P2RX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, P2RX4 versus VRK1 in LSCC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RX4→partner) and Y-score (partner→P2RX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VRK1 →	-0.723	-0.374	<.001	<.001	3	5
GBM	GINS1 →	-0.916	-0.581	<.001	<.001	3	5
UCEC	TICRR →	-0.860	-0.716	<.001	<.001	3	5
UCEC	CCDC150 →	-0.905	-0.628	<.001	<.001	3	5
UCEC	FANCD2 →	-0.872	-0.712	<.001	<.001	3	5
UCEC	DSN1 →	-0.684	-0.545	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,484 associations by consensus.

P2RX4 vs VRK1 — LSCC

Explore this scatter interactively →