P2RX2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, P2RX2 mutation is significantly associated with the RNA expression of many other genes, with 224 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible P2RX2-associated genes across cancer lineages are MIR6799, OCM2, and LINC02770. Each is linked with P2RX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both P2RX2-to-partner and partner-to-P2RX2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RX2→partner) and Y-score (partner→P2RX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMIR6799 →+0.400+5.506.001.00532
CESCOCM2 →+0.094+4.409.001.00632
CESCLINC02770 →+0.071+4.669<.001.00732
LUADOR7E33P →+0.092+4.754<.001.00332
LUADRN7SL837P →+0.135+4.984<.001.00532
UCECRNU4-58P →+0.334+3.548<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 224 associations by consensus.

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