OVOL1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OVOL1 protein abundance is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible OVOL1-associated genes across cancer lineages are ZNF428, HSPA12B, and GSC. Each is linked with OVOL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OVOL1-to-partner and partner-to-OVOL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OVOL1 versus ZNF428 in HNSC, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OVOL1→partner) and Y-score (partner→OVOL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCZNF428 →-0.842-1.288.002.00331
HNSCHSPA12B →-0.994-1.189.001.00931
HNSCGSC →-0.879-1.189<.001.00931
HNSCENPEP →-0.984-1.288.002.00331
HNSCCXADR →+1.712+1.802.006.00931
HNSCELAPOR2 →-0.921-1.294.003.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

OVOL1 vs ZNF428 — HNSC

Per-sample scatter of OVOL1 vs ZNF428 in HNSC (Pearson r = -0.64).

Explore this scatter interactively →

Exploration