OVCH2

Across TCGA cell cohorts, OVCH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 816 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible OVCH2-associated GO terms across cancer lineages are Rho protein signal transduction, Blood coagulation, fibrin clot formation, and Protein activation cascade. Each is linked with OVCH2 in more than 6 cancer types. Because this analysis shows association rather than direction, both OVCH2-to-partner and partner-to-OVCH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rho protein signal transduction grouped by OVCH2-low versus OVCH2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OVCH2→partner) and Y-score (partner→OVCH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Rho protein signal transduction →	+0.072	+0.334	<.001	.008	3	7
BREAST	Blood coagulation, fibrin clot formation →	+0.293	+0.379	<.001	.008	3	7
BREAST	Protein activation cascade →	+0.284	+0.728	<.001	.005	3	6
SKIN	Positive regulation of purine nucleotide biosynthetic process →	+0.098	+0.346	.002	.006	3	6
SKIN	Regulation of potassium ion import →	+0.169	+0.371	<.001	.003	3	6
URINARY_TRACT	Metanephric glomerular mesangium development →	+1.193	+0.892	<.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 816 associations by consensus.

Rho protein signal transduction by OVCH2 expression — SKIN

Explore this box plot interactively →