OVCH2

Across TCGA pan-cancer cohorts, OVCH2 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of OVCH2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OVCH2 RNA is repressed in tumor relative to normal tissue. In most cancer types OVCH2 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and KIRP are the cancer types where OVCH2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OVCH2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	−3.253	<.001	12	view →
KICH	Male	IV	−3.466	<.001	11	view →
KIRP	Male	All	−3.310	<.001	11	view →
LUAD	Female	II,III,IV	−1.892	<.001	11	view →
LUSC	Female	All	−1.457	<.001	7	view →
BRCA	All	III,IV	−1.768	<.001	6	view →
PRAD	All	All	−0.639	<.001	2	view →
UCEC	All	IV	−0.330	.043	2	view →
ESCA	All	All	−0.292	.003	2	view →
THCA	All	IV	+0.187	.030	1	view →
STAD	All	IV	−0.093	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

OVCH2–KIRC

Open the KIRC breakdown →