OTOS

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OTOS mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OTOS-associated genes across cancer lineages are Erythrocytes. Each is linked with OTOS in more than 1 cancer types. Because this analysis shows association rather than direction, both OTOS-to-partner and partner-to-OTOS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by OTOS-low versus OTOS-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OTOS→partner) and Y-score (partner→OTOS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECErythrocytes →+0.039+2.818.006.03531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Erythrocytes by OTOS expression — UCEC

Box plot of Erythrocytes in OTOS-low vs OTOS-high samples in UCEC.

Explore this box plot interactively →

Exploration