Across TCGA patient cohorts, OSTN mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OSTN-associated genes across cancer lineages are RNU6-784P, MIR510, and MTCO1P39. Each is linked with OSTN in more than 1 cancer types. Because this analysis shows association rather than direction, both OSTN-to-partner and partner-to-OSTN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSTN→partner) and Y-score (partner→OSTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-784P →	+0.632	+5.516	<.001	.004	3	2
COAD	MIR510 →	+1.156	+5.602	<.001	.004	3	1
COAD	MTCO1P39 →	+0.229	+5.893	<.001	.002	3	1
COAD	C9orf135-DT →	+0.061	+5.080	.001	.008	3	1
UCEC	MIR6859-2 →	+0.633	+3.690	<.001	.009	3	1
UCEC	MIR6780B →	+0.870	+4.474	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

OSTN survival (RNA) · tumor vs normal (RNA) · all OSTN data types