OSR1

Across TCGA cell cohorts, OSR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,015 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible OSR1-associated GO terms across cancer lineages are Embryonic skeletal limb joint morphogenesis, Negative regulation of epithelial cell differentiation involved in kidney development, and Limb joint morphogenesis. Each is linked with OSR1 in more than 13 cancer types. Because this analysis shows association rather than direction, both OSR1-to-partner and partner-to-OSR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic skeletal limb joint morphogenesis grouped by OSR1-low versus OSR1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OSR1→partner) and Y-score (partner→OSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Embryonic skeletal limb joint morphogenesis →	-0.262	-1.624	<.001	.004	3	14
URINARY_TRACT	Negative regulation of epithelial cell differentiation involved in kidney development →	-0.281	-1.142	<.001	<.001	2	13
LUNG_NSCLC_LUSC	Limb joint morphogenesis →	-0.250	-1.540	<.001	.001	3	10
OVARY	Regulation of gastrulation →	-0.158	-0.721	<.001	.005	3	9
LARGE_INTESTINE	Mesenchymal cell differentiation involved in kidney development →	-0.325	-1.065	<.001	<.001	3	8
LARGE_INTESTINE	Metanephric mesenchymal cell differentiation →	-0.328	-1.114	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,015 associations by consensus.

Embryonic skeletal limb joint morphogenesis by OSR1 expression — BONE

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