OR8D4

Across TCGA patient cohorts, OR8D4 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OR8D4-associated genes across cancer lineages are Macrophages M1, aDC, and DC. Each is linked with OR8D4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8D4-to-partner and partner-to-OR8D4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macrophages M1 grouped by OR8D4-low versus OR8D4-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8D4→partner) and Y-score (partner→OR8D4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Macrophages M1 →	-0.029	-2.988	.043	.037	3	2
LUAD	aDC →	-0.149	-2.976	.009	.037	1	2
LUSC	DC →	-0.024	-3.146	.047	.020	1	2
LUAD	Macrophages →	-0.048	-3.000	.026	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Macrophages M1 by OR8D4 expression — LUAD

Explore this box plot interactively →