OR7G3

Across TCGA patient cohorts, OR7G3 mutation is significantly associated with the RNA expression of many other genes, with 320 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR7G3-associated genes across cancer lineages are OR5T2, LINC02854, and RNU2-60P. Each is linked with OR7G3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7G3-to-partner and partner-to-OR7G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5T2 grouped by OR7G3-low versus OR7G3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7G3→partner) and Y-score (partner→OR7G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OR5T2 →	+0.062	+3.491	.001	.008	3	2
LUAD	LINC02854 →	+0.144	+6.924	<.001	<.001	3	2
LUAD	RNU2-60P →	+0.410	+3.415	<.001	.009	3	2
LUAD	MIR4306 →	+1.003	+4.236	<.001	<.001	3	2
LUAD	RN7SL290P →	+0.193	+4.584	<.001	.005	3	2
LUAD	RN7SL656P →	+0.130	+4.315	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 320 associations by consensus.

OR5T2 by OR7G3 expression — LUAD

Explore this box plot interactively →