OR7G3

Across TCGA pan-cancer cohorts, OR7G3 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated OR7G3 data layer compared with 3 for mutation status.

The strongest signal is observed in small cell lung cancer (SCLC), where higher OR7G3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR7G3 expression acts as an unfavorable survival marker, although some lineages such as ESCA and HNSC show a favorable association.

SCLC, LUSC, and SKCM are the cancer types where OR7G3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	DFS	Tertile	All	0.247	0.818	.007	45	view →
LUSC	DFS	Tertile	II,III,IV	0.079	0.750	<.001	36	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	36	view →
BLCA	DFS	Tertile	IV	0.287	0.480	.019	18	view →
ESCA	DFS	Quartile	III,IV	0.501	0.280	.033	15	view →
LIHC	OS	Tertile	III,IV	0.213	0.648	.042	9	view →
UCEC	DFS	Tertile	All	0.535	0.657	.046	6	view →
HNSC	DFS	Tertile	All	0.598	0.336	.048	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

OR7G3–SCLC (DFS)

Open the SCLC breakdown →