RNA, U2 small nuclear 60, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU2-60P profile across patient tissues and cancer cell-line models. RNU2-60P expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in READ. Among the 18 cancer types available for tumor–normal comparison, RNU2-60P is differentially expressed in 1, with the highest sampling consensus in BLCA. Additionally, RNU2-60P RNA expression shows 11,126 significant gene co-expression associations, with the highest sampling consensus in HNSC. Together, these results highlight READ, BLCA, and HNSC as cancer lineages where RNU2-60P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU2-60P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU2-60P survival associations across molecular data types. RNU2-60P RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU2-60P RNA expression–survival associations across cancer types. High RNU2-60P expression shows unfavorable associations in READ, ESCA, CESC, KIRC, BRCA and LAML. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for RNU2-60P RNA expression.
This table summarizes RNU2-60P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNU2-60P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU2-60P shows higher tumor expression in BLCA. The BLCA box plot shows higher RNU2-60P RNA expression in tumor versus normal tissue (log2 FC = +0.309, t-test p = .019).
This table shows molecular features associated with RNU2-60P in patient tissues and cancer cell lines. In patient samples, RNU2-60P shows the broadest associations at the RNA and protein expression levels, with HNSC recurring as the lineage with the largest associated feature set.
