OR7C2

Across TCGA patient cohorts, OR7C2 mutation is significantly associated with the RNA expression of many other genes, with 1,304 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR7C2-associated genes across cancer lineages are ANXA5, NDUFB6, and PHB. Each is linked with OR7C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7C2-to-partner and partner-to-OR7C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANXA5 grouped by OR7C2-low versus OR7C2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7C2→partner) and Y-score (partner→OR7C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANXA5 →	+0.552	+2.233	.001	.006	3	2
UCEC	NDUFB6 →	+0.453	+3.332	.007	.005	3	2
UCEC	PHB →	+0.527	+2.906	.007	.002	3	2
UCEC	SLC3A2 →	+0.636	+2.265	<.001	.006	3	2
UCEC	NDUFS5 →	+0.412	+2.971	.007	<.001	3	2
UCEC	SLC25A30 →	+0.485	+3.212	.007	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,304 associations by consensus.

ANXA5 by OR7C2 expression — UCEC

Explore this box plot interactively →