Across TCGA pan-cancer cohorts, OR7C2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of OR7C2’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where OR7C2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR7C2 is over-expressed in tumor.
UCEC are the cancer types where OR7C2 tumor–normal differential expression is most reproducible.