OR7C1

Across TCGA patient cohorts, OR7C1 mutation is significantly associated with the RNA expression of many other genes, with 545 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR7C1-associated genes across cancer lineages are TRBJ2-2, MIR6766, and LINC01097. Each is linked with OR7C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7C1-to-partner and partner-to-OR7C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRBJ2-2 grouped by OR7C1-low versus OR7C1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7C1→partner) and Y-score (partner→OR7C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRBJ2-2 →	+1.089	+2.728	.001	.001	3	2
BRCA	MIR6766 →	+0.313	+4.575	.002	.009	3	1
READ	LINC01097 →	+0.025	+4.724	<.001	.003	3	1
UCEC	IGHV3OR16-8 →	+0.722	+3.120	.002	.001	3	1
UCEC	VDAC3P1 →	+0.297	+2.743	.003	.003	3	1
UCEC	IGKV1OR2-6 →	+0.859	+2.688	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 545 associations by consensus.

TRBJ2-2 by OR7C1 expression — UCEC

Explore this box plot interactively →