OR7C1

Across TCGA pan-cancer cohorts, OR7C1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of OR7C1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where OR7C1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR7C1 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

THCA, BRCA, and LUSC are the cancer types where OR7C1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR7C1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	+0.103	<.001	7	view →
BRCA	All	III,IV	−0.626	<.001	6	view →
LUSC	All	All	+0.551	<.001	6	view →
HNSC	All	IV	+0.493	.012	6	view →
KICH	All	All	−0.171	.004	5	view →
BLCA	All	III,IV	+0.211	.027	3	view →
PRAD	All	All	−0.554	<.001	2	view →
KIRC	All	II,III,IV	−0.075	.015	2	view →
COAD	All	II,III,IV	+0.034	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

OR7C1–THCA

Open the THCA breakdown →