Across TCGA cell cohorts, OR6C75 mutation is significantly associated with the RNA expression of many other genes, with 126 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR6C75-associated genes across cancer lineages are ECRG4, DMRTC2, and STRA8. Each is linked with OR6C75 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C75-to-partner and partner-to-OR6C75 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C75→partner) and Y-score (partner→OR6C75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ECRG4 →	+0.083	+3.866	<.001	.006	3	1
LUNG_NSCLC_LUAD	DMRTC2 →	+0.327	+4.215	<.001	.002	3	1
LUNG_NSCLC_LUAD	STRA8 →	+0.450	+4.959	<.001	<.001	3	1
LUNG_NSCLC_LUAD	OR13C8 →	+0.021	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	LCE2C →	+0.025	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	DPPA5 →	+0.049	+3.544	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 126 associations by consensus.

Exploration

OR6C75 survival (RNA) · tumor vs normal (RNA) · all OR6C75 data types