OR5T2

Across TCGA cell cohorts, OR5T2 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR5T2-associated genes across cancer lineages are FAM25G, EPPIN, and ACTRT1. Each is linked with OR5T2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5T2-to-partner and partner-to-OR5T2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM25G grouped by OR5T2-low versus OR5T2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5T2→partner) and Y-score (partner→OR5T2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FAM25G →	+0.662	+4.643	.003	.003	3	1
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	ACTRT1 →	+0.038	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TRIM42 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR10G3 →	+0.035	+5.201	<.001	.006	3	1
BLOOD_Leukemia	SLC22A12 →	+0.006	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

FAM25G by OR5T2 expression — CNS

Explore this box plot interactively →