OR5T2

Across TCGA pan-cancer cohorts, OR5T2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated OR5T2 data layer compared with 7 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher OR5T2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR5T2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and ESCA show a favorable association.

BRCA, LIHC, and READ are the cancer types where OR5T2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.845	0.929	.002	78	view →
LIHC	OS	Tertile	II,III,IV	0.051	0.716	<.001	72	view →
READ	DFS	Tertile	All	0.055	0.854	<.001	72	view →
BLCA	DFS	Tertile	All	0.175	0.526	<.001	45	view →
SARC	OS	Tertile	All	0.108	0.827	<.001	45	view →
STAD	DFS	Tertile	All	0.121	0.503	.006	36	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
SKCM	DFS	Tertile	All	0.892	0.719	.005	30	view →
PCPG	DFS	Tertile	All	0.070	0.936	<.001	18	view →
CESC	DFS	Tertile	II,III,IV	0.193	0.705	.045	18	view →
TGCT	DFS	Tertile	II,III,IV	0.088	0.917	.010	18	view →
ESCA	OS	Tertile	II,III,IV	0.839	0.442	.027	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

OR5T2–BRCA (OS)

Open the BRCA breakdown →