OR5H6

Across TCGA patient cohorts, OR5H6 mutation is significantly associated with the RNA expression of many other genes, with 1,214 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5H6-associated genes across cancer lineages are ZNF70P1, IGHJ1P, and FABP7P2. Each is linked with OR5H6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5H6-to-partner and partner-to-OR5H6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF70P1 grouped by OR5H6-low versus OR5H6-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5H6→partner) and Y-score (partner→OR5H6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF70P1 →	+0.207	+5.310	<.001	.001	3	2
HNSC	IGHJ1P →	+1.015	+4.197	<.001	.009	3	2
HNSC	FABP7P2 →	+0.205	+4.425	.001	.006	3	2
HNSC	KIR2DP1 →	+0.240	+4.425	<.001	.006	3	2
HNSC	RNU6-1137P →	+0.372	+4.505	<.001	.009	3	2
STAD	RNU6-326P →	+0.553	+4.480	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,214 associations by consensus.

ZNF70P1 by OR5H6 expression — HNSC

Explore this box plot interactively →