OR5H6

Across TCGA cell cohorts, OR5H6 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR5H6-associated genes across cancer lineages are HMGB4, REG1B, and SPINK14. Each is linked with OR5H6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5H6-to-partner and partner-to-OR5H6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HMGB4 grouped by OR5H6-low versus OR5H6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5H6→partner) and Y-score (partner→OR5H6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HMGB4 →	+0.039	+5.539	<.001	.003	3	1
LUNG_NSCLC_LUAD	REG1B →	+0.037	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	SPINK14 →	+0.264	+4.662	<.001	.005	3	1
SKIN	USP17L17 →	+0.013	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

HMGB4 by OR5H6 expression — BLOOD_Leukemia

Explore this box plot interactively →