OR5H2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR5H2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OR5H2-associated genes across cancer lineages are CLDN34, C10orf53, and VN1R2. Each is linked with OR5H2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5H2-to-partner and partner-to-OR5H2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5H2→partner) and Y-score (partner→OR5H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaCLDN34 →+0.043+4.807<.001.00631
CNSC10orf53 →+0.083+5.044<.001.00131
CNSVN1R2 →+0.035+4.643<.001.00331
CNSVN1R4 →+0.073+4.754<.001.00531
CNSTARM1 →+0.013+4.321.002.00931
LUNG_SCLCOR2T7 →+0.006+5.643<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

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