OR5B12

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR5B12 mutation is significantly associated with the RNA expression of many other genes, with 698 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5B12-associated genes across cancer lineages are RNU6-1155P, RPL15P3, and DUOX1. Each is linked with OR5B12 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5B12-to-partner and partner-to-OR5B12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1155P grouped by OR5B12-low versus OR5B12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B12→partner) and Y-score (partner→OR5B12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-1155P →+0.106+4.253.005.00433
SKCMRPL15P3 →+0.378+2.235.003.00533
LUSCDUOX1 →-0.927-2.783.001.00333
LIHCRN7SL787P →+0.156+6.902<.001<.00132
LIHCMIR3135A →+0.451+5.355<.001.00532
LIHCRNA5SP65 →+0.331+6.305<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 698 associations by consensus.

RNU6-1155P by OR5B12 expression — UCEC

Box plot of RNU6-1155P in OR5B12-low vs OR5B12-high samples in UCEC.

Explore this box plot interactively →

Exploration