OR5B12

Across TCGA patient cohorts, OR5B12 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5B12-associated genes across cancer lineages are Annexin-1, TAZ, and ASNS. Each is linked with OR5B12 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5B12-to-partner and partner-to-OR5B12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by OR5B12-low versus OR5B12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B12→partner) and Y-score (partner→OR5B12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.635	+3.019	.012	.019	3	2
SKCM	TAZ →	+0.145	+1.597	.017	.040	3	2
LUSC	ASNS →	+0.678	+2.816	.005	.036	3	1
LUSC	c-Met_pY1235 →	+0.153	+2.816	<.001	.036	2	2
LUAD	PDCD4 →	+0.451	+2.819	.040	.035	3	1
UCEC	Notch1 →	+0.149	+3.179	.028	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Annexin-1 by OR5B12 expression — UCEC

Explore this box plot interactively →