OR5B12

Across TCGA cell cohorts, OR5B12 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR5B12-associated genes across cancer lineages are OR10Q1, IFNA2, and PRAMEF10. Each is linked with OR5B12 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5B12-to-partner and partner-to-OR5B12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10Q1 grouped by OR5B12-low versus OR5B12-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B12→partner) and Y-score (partner→OR5B12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR10Q1 →	+0.653	+5.643	<.001	.002	3	1
LUNG_SCLC	IFNA2 →	+0.019	+5.029	<.001	.006	3	1
LUNG_NSCLC_LUAD	PRAMEF10 →	+0.012	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	CCL18 →	+0.032	+4.212	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR10Q1 by OR5B12 expression — LUNG_SCLC

Explore this box plot interactively →